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Experience

From the start of the company in 1987 we have carried out more than 300 projects.

Of these, 60 were statistical evaluations and reports in the start-up phase, and 124 were full service clinical trials (from protocol to final report) in more than 7,000 patients. In a further 120 projects we provided partial services (monitoring, medical writing, data management, regulatory affairs).

Below are listed full-service projects in the last 5 years.

Indication

Number of studies

Haematology

Haemophilia A

1

Haemophilia B

3

Von Willebrandt disease

3

Alpha-1-Aminotrypsin-deficiency

1

Allergology

Pollen allergy

3

Surgery

Vascular surgery

3

Other surgery

4

Neurology

Parkinson’s disease

3

Narcolepsy

1

Polyneuropathy

1

Rheumatology

Osteoarthritis

2

Arthritis

4

Oncology

Pain relief in cancer

3

Prostatic cancer

3

Breast cancer

1

Ophthalmology

Conjunctivitis

2

Diabetic retinopathy

2

Cardiology

Hypertension

2

Gastroenterology

Ulcerative Colitis

3

Hepatitis C

4

Others

Radioactive contamination

2

Transplantation

1

Premature labour

1

Scintigraphy

1

Phase I

4

Moreover, Clinical Investigations Ltd has experience in the following indications.

Ophthalmology

Inflammatory diseases, postoperative infection prevention, glaucoma, cataract operations, analgesia following injuries to the cornea, senile macular degeneration

Allergology

House dust mites, neurodermitis, pollen allergy, non-seasonal allergies

Dermatology

Psoriasis, eczema, dermatitis, cold sores, crural ulcers, mycosis, pressure ulcer

Cardiology

Hypertension, coronary heart disease, heart failure, cardiac arrhythmias, stent implantation, IVUS

Urology

Infections, benign prostatic diseases

Pulmonology

Bronchial asthma, bronchitis, emphysema, allergic asthma

Gastroenterology

Gastropathies, gastric and duodenal ulcers

Endocrinology

Diabetes, adrenal dysfunction

Gynaecology

Endometriosis, mastopathy, premenstrual syndrome, menopausal syndrome

Neurology

Diabetic and alcoholic neuropathies, multiple sclerosis

Psychiatry

Schizophrenia, schizophreniform disorders, depression, anxiety

Others

Arterial and venous vascular diseases, disorders of lipid metabolism, headache and migraine, xerostomia, infectious and inflammatory diseases, anaesthesia, pain treatment, intensive care, diabetes, etc.

Phase I

Bioequivalence studies
Pharmacokinetic studies in patients (e.g. in asthmatics, the elderly, those with immunological, liver or kidney diseases)

Countries where studies were carried

Countries

Trials

Number of patients

Bulgaria

6

450

Czech Republic

1

120

Hungary

15

1,120

Poland

2

120

Romania

8

700

Two or more countries

16

1,410

All countries

1

360

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